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DNA Methylation of Heparanase Promoter Influences Its Expression and Associated with the Progression of Human Breast Cancer

Heparanase promotes tumor invasion and metastasis in several malignancies including breast cancer. However, the roles and regulation mechanisms of heparanase during breast cancer progression are still not fully understood. The aim of this study is to determine the differential regulation of heparana...

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Detalles Bibliográficos
Autores principales: Jiao, Fei, Bai, Shi-yu, Ma, Ying, Yan, Zhong-hai, Yue, Zhen, Yu, Yuan, Wang, Xin, Wang, Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954879/
https://www.ncbi.nlm.nih.gov/pubmed/24632672
http://dx.doi.org/10.1371/journal.pone.0092190