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L-Myc expression by dendritic cells is required for optimal T-cell priming

The transcription factors c-Myc and N-Myc encoded by Myc and Mycn, respectively, regulate cellular growth(1) and are required for embryonic development(2,3). A third paralog, Mycl1, is dispensable for normal embryonic development but its normal biologic function has remained unclear(4). To examine t...

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Detalles Bibliográficos
Autores principales: Wumesh, KC, Satpathy, Ansuman T., Rapaport, Aaron S., Briseño, Carlos G., Wu, Xiaodi, Albring, Jörn C., Russler-Germain, Emilie V., Kretzer, Nicole M., Durai, Vivek, Persaud, Stephen P., Edelson, Brian T., Loschko, Jakob, Cella, Marina, Allen, Paul M., Nussenzweig, Michel C., Colonna, Marco, Sleckman, Barry P., Murphy, Theresa L., Murphy, Kenneth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954917/
https://www.ncbi.nlm.nih.gov/pubmed/24509714
http://dx.doi.org/10.1038/nature12967