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Mathematical Modeling of Interleukin-27 Induction of Anti-Tumor T Cells Response

Interleukin-12 is a pro-inflammatory cytokine which promotes Th1 and cytotoxic T lymphocyte activities, such as Interferon-[Image: see text] secretion. For this reason Interleukin-12 could be a powerful therapeutic agent for cancer treatment. However, Interleukin-12 is also excessively toxic. Interl...

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Detalles Bibliográficos
Autores principales: Liao, Kang-Ling, Bai, Xue-Feng, Friedman, Avner
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954918/
https://www.ncbi.nlm.nih.gov/pubmed/24633175
http://dx.doi.org/10.1371/journal.pone.0091844