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Inflammatory cytokines promote growth of intestinal smooth muscle cells by induced expression of PDGF-Rβ
Thickening of the inflamed intestinal wall involves growth of smooth muscle cells (SMC), which contributes to stricture formation. Earlier, the growth factor platelet-derived growth factor (PDGF)-BB was identified as a key mitogen for SMC from the rat colon (CSMC), and CSMC growth in colitis was ass...
Autores principales: | Nair, Dileep G, Miller, Kurtis G, Lourenssen, Sandra R, Blennerhassett, Michael G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955151/ https://www.ncbi.nlm.nih.gov/pubmed/24417820 http://dx.doi.org/10.1111/jcmm.12193 |
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