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Influence of type-I Interferon receptor expression level on the response to type-I Interferons in human pancreatic cancer cells

Pancreatic cancer is a highly aggressive malignancy with limited treatment options. Type-I interferons (e.g. IFN-α/-β) have several anti-tumour activities. Over the past few years, clinical studies evaluating the effect of adjuvant IFN-α therapy in pancreatic cancer yielded equivocal results. Althou...

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Detalles Bibliográficos
Autores principales: Booy, Stephanie, van Eijck, Casper H J, Dogan, Fadime, van Koetsveld, Peter M, Hofland, Leo J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955155/
https://www.ncbi.nlm.nih.gov/pubmed/24460759
http://dx.doi.org/10.1111/jcmm.12200