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MicroRNA-based discovery of barriers to dedifferentiation of fibroblasts to pluripotent stem cells

Individual microRNAs (miRNAs) can target hundreds of messenger RNAs forming networks of presumably cooperating genes. To test this presumption, we functionally screened miRNAs and their targets in the context of de-differentiation of mouse fibroblasts to induced pluripotent stem cells (iPSCs). Along...

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Detalles Bibliográficos
Autores principales: Judson, Robert L, Greve, Tobias S, Parchem, Ronald J, Blelloch, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955211/
https://www.ncbi.nlm.nih.gov/pubmed/24037508
http://dx.doi.org/10.1038/nsmb.2665