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MicroRNA-based discovery of barriers to dedifferentiation of fibroblasts to pluripotent stem cells
Individual microRNAs (miRNAs) can target hundreds of messenger RNAs forming networks of presumably cooperating genes. To test this presumption, we functionally screened miRNAs and their targets in the context of de-differentiation of mouse fibroblasts to induced pluripotent stem cells (iPSCs). Along...
Autores principales: | Judson, Robert L, Greve, Tobias S, Parchem, Ronald J, Blelloch, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955211/ https://www.ncbi.nlm.nih.gov/pubmed/24037508 http://dx.doi.org/10.1038/nsmb.2665 |
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