Comparison of Heavy Labeled (SIL) Peptide versus SILAC Protein Internal Standards for LC-MS/MS Quantification of Hepatic Drug Transporters

We studied the precision of quantification of organic anion-transporting polypeptide 1B1 (OATP1B1), OATP1B3, OATP2B1, and P-glycoprotein (P-gp) in human livers by surrogate peptide based LC-MS/MS approach using two different internal standards: stable isotope labeled peptide (SIL) versus stable isot...

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Detalles Bibliográficos
Autores principales: Prasad, Bhagwat, Unadkat, Jashvant D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955635/
https://www.ncbi.nlm.nih.gov/pubmed/24719762
http://dx.doi.org/10.1155/2014/451510

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955635/
https://www.ncbi.nlm.nih.gov/pubmed/24719762
http://dx.doi.org/10.1155/2014/451510

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