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Synthesis and Characterization of Folate-Targeted Dextran/Retinoic Acid Micelles for Doxorubicin Delivery in Acute Leukemia

Folate and retinoic acid grafted/dextran (FA-RA/DEX) copolymers with different molecular weight of DEX were synthesized using carbonyldiimidazole and dimethylaminopyridine for targeted delivery of doxorubicin (DOX) in acute myelogenous leukemia (AML). The copolymers structure was confirmed by (1)H N...

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Detalles Bibliográficos
Autores principales: Varshosaz, J., Hassanzadeh, F., Sadeghi Aliabadi, H., Nayebsadrian, M., Banitalebi, M., Rostami, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955650/
https://www.ncbi.nlm.nih.gov/pubmed/24719872
http://dx.doi.org/10.1155/2014/525684