PD-1 modulates steady-state and infection-induced IL-10 production in vivo

Programmed death-1 (PD-1) plays an important role in mediating immune tolerance through mechanisms that remain unclear. Herein, we investigated whether PD-1 prevents excessive host tissue damage during infection with the protozoan parasite, Toxoplasma gondii. Surprisingly, our results demonstrate th...

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Detalles Bibliográficos
Autores principales: McBerry, Cortez, Dias, Alexandra, Shryock, Nathaniel, Lampe, Kristin, Gutierrez, Fredy R S, Boon, Louis, Herbert, De’Broski R, Aliberti, Julio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Immunomodulation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955717/
https://www.ncbi.nlm.nih.gov/pubmed/24165808
http://dx.doi.org/10.1002/eji.201343658

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3955717/
https://www.ncbi.nlm.nih.gov/pubmed/24165808
http://dx.doi.org/10.1002/eji.201343658

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