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Pathway Analysis for Drug Repositioning Based on Public Database Mining

[Image: see text] Sixteen FDA-approved drugs were investigated to elucidate their mechanisms of action (MOAs) and clinical functions by pathway analysis based on retrieved drug targets interacting with or affected by the investigated drugs. Protein and gene targets and associated pathways were obtai...

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Detalles Bibliográficos
Autores principales: Pan, Yongmei, Cheng, Tiejun, Wang, Yanli, Bryant, Stephen H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956470/
https://www.ncbi.nlm.nih.gov/pubmed/24460210
http://dx.doi.org/10.1021/ci4005354