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Pathway Analysis for Drug Repositioning Based on Public Database Mining
[Image: see text] Sixteen FDA-approved drugs were investigated to elucidate their mechanisms of action (MOAs) and clinical functions by pathway analysis based on retrieved drug targets interacting with or affected by the investigated drugs. Protein and gene targets and associated pathways were obtai...
Autores principales: | Pan, Yongmei, Cheng, Tiejun, Wang, Yanli, Bryant, Stephen H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956470/ https://www.ncbi.nlm.nih.gov/pubmed/24460210 http://dx.doi.org/10.1021/ci4005354 |
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