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Molecular Recognition of the Neurotransmitter Acetylcholine by an Acetylcholine Binding Protein Reveals Determinants of Binding to Nicotinic Acetylcholine Receptors

Despite extensive studies on nicotinic acetylcholine receptors (nAChRs) and homologues, details of acetylcholine binding are not completely resolved. Here, we report the crystal structure of acetylcholine bound to the receptor homologue acetylcholine binding protein from Lymnaea stagnalis. This is t...

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Detalles Bibliográficos
Autores principales: Olsen, Jeppe A., Balle, Thomas, Gajhede, Michael, Ahring, Philip K., Kastrup, Jette S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956608/
https://www.ncbi.nlm.nih.gov/pubmed/24637639
http://dx.doi.org/10.1371/journal.pone.0091232