DNA-Damage Foci to Detect and Characterize DNA Repair Alterations in Children Treated for Pediatric Malignancies

PURPOSE: In children diagnosed with cancer, we evaluated the DNA damage foci approach to identify patients with double-strand break (DSB) repair deficiencies, who may overreact to DNA-damaging radio- and chemotherapy. In one patient with Fanconi anemia (FA) suffering relapsing squamous cell carcinom...

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Detalles Bibliográficos
Autores principales: Schuler, Nadine, Palm, Jan, Kaiser, Mareike, Betten, Dominik, Furtwängler, Rhoikos, Rübe, Christian, Graf, Norbert, Rübe, Claudia E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956609/
https://www.ncbi.nlm.nih.gov/pubmed/24637877
http://dx.doi.org/10.1371/journal.pone.0091319

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956609/
https://www.ncbi.nlm.nih.gov/pubmed/24637877
http://dx.doi.org/10.1371/journal.pone.0091319

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