Cargando…

Short Peptides as Inhibitors of Amyloid Aggregation

The misfolding and aggregation of proteins into amyloid has been linked to a variety of age-related diseases. Aggregation of proteins, such as Aβ in Alzheimer’s disease and Islet Amyloid Polypeptide (IAPP, amylin) in type 2 diabetes, appears to lead to the formation of toxic assemblies. These assemb...

Descripción completa

Detalles Bibliográficos
Autores principales: Neddenriep, Bradley, Calciano, Anastasia, Conti, Daniel, Sauve, Erin, Paterson, Marissa, Bruno, Edward, Moffet, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956661/
https://www.ncbi.nlm.nih.gov/pubmed/24653784
http://dx.doi.org/10.2174/1874070701105010039