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Short Peptides as Inhibitors of Amyloid Aggregation
The misfolding and aggregation of proteins into amyloid has been linked to a variety of age-related diseases. Aggregation of proteins, such as Aβ in Alzheimer’s disease and Islet Amyloid Polypeptide (IAPP, amylin) in type 2 diabetes, appears to lead to the formation of toxic assemblies. These assemb...
Autores principales: | Neddenriep, Bradley, Calciano, Anastasia, Conti, Daniel, Sauve, Erin, Paterson, Marissa, Bruno, Edward, Moffet, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956661/ https://www.ncbi.nlm.nih.gov/pubmed/24653784 http://dx.doi.org/10.2174/1874070701105010039 |
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