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Integrated Analysis of DNA Methylation and RNA Transcriptome during In Vitro Differentiation of Human Pluripotent Stem Cells into Retinal Pigment Epithelial Cells

Using the paradigm of in vitro differentiation of hESCs/iPSCs into retinal pigment epithelial (RPE) cells, we have recently profiled mRNA and miRNA transcriptomes to define a set of RPE mRNA and miRNA signature genes implicated in directed RPE differentiation. In this study, in order to understand t...

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Detalles Bibliográficos
Autores principales: Liu, Zhenshan, Jiang, Rongfeng, Yuan, Songtao, Wang, Na, Feng, Yun, Hu, Ganlu, Zhu, Xianmin, Huang, Kevin, Ma, Jieliang, Xu, Guotong, Liu, Qinghuai, Xue, Zhigang, Fan, Guoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956675/
https://www.ncbi.nlm.nih.gov/pubmed/24638073
http://dx.doi.org/10.1371/journal.pone.0091416