Gene Silencing of SOCS3 by siRNA Intranasal Delivery Inhibits Asthma Phenotype in Mice

Suppresors of cytokine signaling (SOCS) proteins regulate cytokine responses and control immune balance. Several studies have confirmed that SOCS3 is increased in asthmatic patients, and SOCS3 expression is correlated with disease severity. The objective of this study was to evaluate if delivering o...

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Detalles Bibliográficos
Autores principales: Mazzeo, Carla, Gámez, Cristina, Rodriguez Marco, Ainara, de Zulueta, Ana, Sanz, Veronica, Bilbao, Izaskun, Ruiz-Cabello, Jesús, Zubeldia, Jose M., del Pozo, Victoria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956882/
https://www.ncbi.nlm.nih.gov/pubmed/24637581
http://dx.doi.org/10.1371/journal.pone.0091996

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956882/
https://www.ncbi.nlm.nih.gov/pubmed/24637581
http://dx.doi.org/10.1371/journal.pone.0091996

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