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Gene Silencing of SOCS3 by siRNA Intranasal Delivery Inhibits Asthma Phenotype in Mice
Suppresors of cytokine signaling (SOCS) proteins regulate cytokine responses and control immune balance. Several studies have confirmed that SOCS3 is increased in asthmatic patients, and SOCS3 expression is correlated with disease severity. The objective of this study was to evaluate if delivering o...
Autores principales: | Mazzeo, Carla, Gámez, Cristina, Rodriguez Marco, Ainara, de Zulueta, Ana, Sanz, Veronica, Bilbao, Izaskun, Ruiz-Cabello, Jesús, Zubeldia, Jose M., del Pozo, Victoria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956882/ https://www.ncbi.nlm.nih.gov/pubmed/24637581 http://dx.doi.org/10.1371/journal.pone.0091996 |
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