Rifampicin Protects PC12 Cells from Rotenone-Induced Cytotoxicity by Activating GRP78 via PERK-eIF2α-ATF4 Pathway

Rifampicin has been proposed as a therapeutic candidate for Parkinson's disease (PD). We previously showed that rifampicin was neuroprotective in PD models in vivo and in vitro. However, the molecular mechanisms underlying are not fully elucidated. In this study, using the comprehensive proteom...

Descripción completa

Detalles Bibliográficos
Autores principales: Jing, Xiuna, Shi, Qiaoyun, Bi, Wei, Zeng, Zhifen, Liang, Yanran, Wu, Xia, Xiao, Songhua, Liu, Jun, Yang, Lianhong, Tao, Enxiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956889/
https://www.ncbi.nlm.nih.gov/pubmed/24638036
http://dx.doi.org/10.1371/journal.pone.0092110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956889/
https://www.ncbi.nlm.nih.gov/pubmed/24638036
http://dx.doi.org/10.1371/journal.pone.0092110

Ejemplares similares