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De Novo Structure Prediction of Globular Proteins Aided by Sequence Variation-Derived Contacts

The advent of high accuracy residue-residue intra-protein contact prediction methods enabled a significant boost in the quality of de novo structure predictions. Here, we investigate the potential benefits of combining a well-established fragment-based folding algorithm – FRAGFOLD, with PSICOV, a co...

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Detalles Bibliográficos
Autores principales: Kosciolek, Tomasz, Jones, David T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956894/
https://www.ncbi.nlm.nih.gov/pubmed/24637808
http://dx.doi.org/10.1371/journal.pone.0092197