Postsynaptic Target Specific Synaptic Dysfunctions in the CA3 Area of BACE1 Knockout Mice

Beta-amyloid precursor protein cleaving enzyme 1 (BACE1), a major neuronal β-secretase critical for the formation of β-amyloid (Aβ) peptide, is considered one of the key therapeutic targets that can prevent the progression of Alzheimer’s disease (AD). Although a complete ablation of BACE1 gene preve...

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Detalles Bibliográficos
Autores principales: Wang, Hui, Megill, Andrea, Wong, Philip C., Kirkwood, Alfredo, Lee, Hey-Kyoung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956924/
https://www.ncbi.nlm.nih.gov/pubmed/24637500
http://dx.doi.org/10.1371/journal.pone.0092279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956924/
https://www.ncbi.nlm.nih.gov/pubmed/24637500
http://dx.doi.org/10.1371/journal.pone.0092279

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