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Rho-Kinase Activation in Leukocytes Plays a Pivotal Role in Myocardial Ischemia/Reperfusion Injury

The Rho/Rho-kinase pathway plays an important role in many cardiovascular diseases such as hypertension, atherosclerosis, heart failure, and myocardial infarction. Although previous studies have shown that Rho-kinase inhibitors reduce ischemia/reperfusion (I/R) injury and cytokine production, the ro...

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Detalles Bibliográficos
Autores principales: Kitano, Katsunori, Usui, Soichiro, Ootsuji, Hiroshi, Takashima, Shin-ichiro, Kobayashi, Daisuke, Murai, Hisayoshi, Furusho, Hiroshi, Nomura, Ayano, Kaneko, Shuichi, Takamura, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956925/
https://www.ncbi.nlm.nih.gov/pubmed/24638037
http://dx.doi.org/10.1371/journal.pone.0092242