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Signaling control of the constitutive androstane receptor (CAR)

The constitutive androstane receptor (CAR, NR1I3) plays a crucial role in the regulation of drug metabolism, energy homeostasis, and cancer development through modulating the transcription of its numerous target genes. Different from prototypical nuclear receptors, CAR can be activated by either dir...

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Detalles Bibliográficos
Autores principales: Yang, Hui, Wang, Hongbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956974/
https://www.ncbi.nlm.nih.gov/pubmed/24474196
http://dx.doi.org/10.1007/s13238-013-0013-0