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Crystal structure of E. coli arginyl-tRNA synthetase and ligand binding studies revealed key residues in arginine recognition

The arginyl-tRNA synthetase (ArgRS) catalyzes the esterification reaction between L-arginine and its cognate tRNA(Arg). Previously reported structures of ArgRS shed considerable light on the tRNA recognition mechanism, while the aspect of amino acid binding in ArgRS remains largely unexplored. Here...

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Detalles Bibliográficos
Autores principales: Bi, Kelei, Zheng, Yueting, Gao, Feng, Dong, Jianshu, Wang, Jiangyun, Wang, Yi, Gong, Weimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3956977/
https://www.ncbi.nlm.nih.gov/pubmed/24474195
http://dx.doi.org/10.1007/s13238-013-0012-1