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WaveCNV: allele-specific copy number alterations in primary tumors and xenograft models from next-generation sequencing
Motivation: Copy number variations (CNVs) are a major source of genomic variability and are especially significant in cancer. Until recently microarray technologies have been used to characterize CNVs in genomes. However, advances in next-generation sequencing technology offer significant opportunit...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957071/ https://www.ncbi.nlm.nih.gov/pubmed/24192544 http://dx.doi.org/10.1093/bioinformatics/btt611 |