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The DNMT1/PCNA/UHRF1 disruption induces tumorigenesis characterized by similar genetic and epigenetic signatures

Several genetic and epigenetic signatures characterize cancer cells. However, the relationships (causal or consequence link, existence due to a same origin) between these 2 types of signatures were not fully elucidated. In the present work, we reported that the disruption of the DNMT1/PCNA/UHRF1 com...

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Detalles Bibliográficos
Autores principales: Pacaud, Romain, Brocard, Emeline, Lalier, Lisenn, Hervouet, Eric, Vallette, François M., Cartron, Pierre-François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957150/
https://www.ncbi.nlm.nih.gov/pubmed/24637615
http://dx.doi.org/10.1038/srep04230