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A Mechanistic Investigation of the C-Terminal Redox Motif of Thioredoxin Reductase from Plasmodium falciparum

[Image: see text] High-molecular mass thioredoxin reductases (TRs) are pyridine nucleotide disulfide oxidoreductases that catalyze the reduction of the disulfide bond of thioredoxin (Trx). Trx is responsible for reducing multiple protein disulfide targets in the cell. TRs utilize reduced β-nicotinam...

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Detalles Bibliográficos
Autores principales: Snider, Gregg W., Dustin, Christopher M., Ruggles, Erik L., Hondal, Robert J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957191/
https://www.ncbi.nlm.nih.gov/pubmed/24400600
http://dx.doi.org/10.1021/bi400931k