Cargando…

CaMKII in sinoatrial node physiology and dysfunction

The calcium and calmodulin-dependent protein kinase II (CaMKII) is present in sinoatrial node (SAN) pacemaker cells and is required for physiological “fight or flight” SAN beating rate responses. Inhibition of CaMKII in SAN does not affect baseline heart rate, but reduces heart rate increases in res...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Yuejin, Anderson, Mark E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957193/
https://www.ncbi.nlm.nih.gov/pubmed/24672485
http://dx.doi.org/10.3389/fphar.2014.00048