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Why Is Mammalian Thioredoxin Reductase 1 So Dependent upon the Use of Selenium?
[Image: see text] Cytosolic thioredoxin reductase 1 (TR1) is the best characterized of the class of high-molecular weight (M(r)) thioredoxin reductases (TRs). TR1 is highly dependent upon the rare amino acid selenocysteine (Sec) for the reduction of thioredoxin (Trx) and a host of small molecule sub...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American
Chemical Society
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957196/ https://www.ncbi.nlm.nih.gov/pubmed/24393022 http://dx.doi.org/10.1021/bi400651x |