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Microfluidics-Based Capture of Human Neutrophils for Expression Analysis in Blood and Bronchoalveolar Lavage

Gene expression analysis can be a powerful tool in predicting patient outcomes and identifying patients who may benefit from targeted therapies. However, isolating human blood neutrophils (PMNs) for genomic analysis has been challenging. We employed a novel microfluidic technique that isolates PMNs...

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Detalles Bibliográficos
Autores principales: Warner, Elizabeth A., Kotz, Kenneth, Ungaro, Ricardo, Abouhamze, Amer, Lopez, M. Cecilia, Cuenca, Alex G., Kelly-Scumpia, Kindra M., Moreno, Claudia, O’Malley, Kerri, Lanz, Jennifer D., Baker, Henry V., Martin, Larry C., Toner, Mehmet, Efron, Philip A., Moldawer, Lyle L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957199/
https://www.ncbi.nlm.nih.gov/pubmed/21931299
http://dx.doi.org/10.1038/labinvest.2011.94