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Microfluidics-Based Capture of Human Neutrophils for Expression Analysis in Blood and Bronchoalveolar Lavage
Gene expression analysis can be a powerful tool in predicting patient outcomes and identifying patients who may benefit from targeted therapies. However, isolating human blood neutrophils (PMNs) for genomic analysis has been challenging. We employed a novel microfluidic technique that isolates PMNs...
Autores principales: | Warner, Elizabeth A., Kotz, Kenneth, Ungaro, Ricardo, Abouhamze, Amer, Lopez, M. Cecilia, Cuenca, Alex G., Kelly-Scumpia, Kindra M., Moreno, Claudia, O’Malley, Kerri, Lanz, Jennifer D., Baker, Henry V., Martin, Larry C., Toner, Mehmet, Efron, Philip A., Moldawer, Lyle L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957199/ https://www.ncbi.nlm.nih.gov/pubmed/21931299 http://dx.doi.org/10.1038/labinvest.2011.94 |
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