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A major role for Tau in neuronal DNA and RNA protection in vivo under physiological and hyperthermic conditions
Nucleic acid protection is a substantial challenge for neurons, which are continuously exposed to oxidative stress in the brain. Neurons require powerful mechanisms to protect DNA and RNA integrity and ensure their functionality and longevity. Beside its well known role in microtubule dynamics, we r...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957276/ https://www.ncbi.nlm.nih.gov/pubmed/24672431 http://dx.doi.org/10.3389/fncel.2014.00084 |