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A major role for Tau in neuronal DNA and RNA protection in vivo under physiological and hyperthermic conditions

Nucleic acid protection is a substantial challenge for neurons, which are continuously exposed to oxidative stress in the brain. Neurons require powerful mechanisms to protect DNA and RNA integrity and ensure their functionality and longevity. Beside its well known role in microtubule dynamics, we r...

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Detalles Bibliográficos
Autores principales: Violet, Marie, Delattre, Lucie, Tardivel, Meryem, Sultan, Audrey, Chauderlier, Alban, Caillierez, Raphaelle, Talahari, Smail, Nesslany, Fabrice, Lefebvre, Bruno, Bonnefoy, Eliette, Buée, Luc, Galas, Marie-Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957276/
https://www.ncbi.nlm.nih.gov/pubmed/24672431
http://dx.doi.org/10.3389/fncel.2014.00084