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MERS-CoV papain-like protease has deISGylating and deubiquitinating activities

Coronaviruses encode papain-like proteases (PLpro) that are often multifunctional enzymes with protease activity to process the viral replicase polyprotein and deubiquitinating (DUB)/deISGylating activity, which is hypothesized to modify the innate immune response to infection. Here, we investigate...

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Detalles Bibliográficos
Autores principales:	Mielech, Anna M., Kilianski, Andy, Baez-Santos, Yahira M., Mesecar, Andrew D., Baker, Susan C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Inc. 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957432/ https://www.ncbi.nlm.nih.gov/pubmed/24503068 http://dx.doi.org/10.1016/j.virol.2013.11.040

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