An unappreciated role for RNA surveillance

BACKGROUND: Nonsense-mediated mRNA decay (NMD) is a eukaryotic mRNA surveillance mechanism that detects and degrades mRNAs with premature termination codons (PTC(+ )mRNAs). In mammals, a termination codon is recognized as premature if it lies more than about 50 nucleotides upstream of the final intr...

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Detalles Bibliográficos
Autores principales: Hillman, R Tyler, Green, Richard E, Brenner, Steven E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC395752/
https://www.ncbi.nlm.nih.gov/pubmed/14759258
http://dx.doi.org/10.1186/gb-2004-5-2-r8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC395752/
https://www.ncbi.nlm.nih.gov/pubmed/14759258
http://dx.doi.org/10.1186/gb-2004-5-2-r8

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