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In silico identification and experimental validation of PmrAB targets in Salmonella typhimurium by regulatory motif detection
BACKGROUND: The PmrAB (BasSR) two-component regulatory system is required for Salmonella typhimurium virulence. PmrAB-controlled modifications of the lipopolysaccharide (LPS) layer confer resistance to cationic antibiotic polypeptides, which may allow bacteria to survive within macrophages. The PmrA...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC395753/ https://www.ncbi.nlm.nih.gov/pubmed/14759259 http://dx.doi.org/10.1186/gb-2004-5-2-r9 |