Rosetting Plasmodium falciparum-Infected Erythrocytes Bind to Human Brain Microvascular Endothelial Cells In Vitro, Demonstrating a Dual Adhesion Phenotype Mediated by Distinct P. falciparum Erythrocyte Membrane Protein 1 Domains

Adhesion interactions between Plasmodium falciparum-infected erythrocytes (IE) and human cells underlie the pathology of severe malaria. IE cytoadhere to microvascular endothelium or form rosettes with uninfected erythrocytes to survive in vivo by sequestering IE in the microvasculature and avoiding...

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Detalles Bibliográficos
Autores principales: Adams, Yvonne, Kuhnrae, Pongsak, Higgins, Matthew K., Ghumra, Ashfaq, Rowe, J. Alexandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2014
Materias:
Fungal and Parasitic Infections
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958005/
https://www.ncbi.nlm.nih.gov/pubmed/24343658
http://dx.doi.org/10.1128/IAI.01233-13

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958005/
https://www.ncbi.nlm.nih.gov/pubmed/24343658
http://dx.doi.org/10.1128/IAI.01233-13

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