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193 nm Ultraviolet Photodissociation Mass Spectrometry for the Structural Elucidation of Lipid A Compounds in Complex Mixtures

[Image: see text] Here we implement ultraviolet photodissociation (UVPD) in an online liquid chromatographic tandem mass spectrometry (MS/MS) strategy to support analysis of complex mixtures of lipid A combinatorially modified during development of vaccine adjuvants. UVPD mass spectrometry at 193 nm...

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Detalles Bibliográficos
Autores principales: O’Brien, John P., Needham, Brittany D., Henderson, Jeremy C., Nowicki, Emily M., Trent, M. Stephen, Brodbelt, Jennifer S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958132/
https://www.ncbi.nlm.nih.gov/pubmed/24446701
http://dx.doi.org/10.1021/ac403796n