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Weighted Implementation of Suboptimal Paths (WISP): An Optimized Algorithm and Tool for Dynamical Network Analysis

[Image: see text] Allostery can occur by way of subtle cooperation among protein residues (e.g., amino acids) even in the absence of large conformational shifts. Dynamical network analysis has been used to model this cooperation, helping to computationally explain how binding to an allosteric site c...

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Detalles Bibliográficos
Autores principales: Van Wart, Adam T., Durrant, Jacob, Votapka, Lane, Amaro, Rommie E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958135/
https://www.ncbi.nlm.nih.gov/pubmed/24803851
http://dx.doi.org/10.1021/ct4008603