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Telomerase governs immunomodulatory properties of mesenchymal stem cells by regulating FAS ligand expression

Bone marrow mesenchymal stem cells (BMMSCs) are capable of differentiating into multiple cell types and regulating immune cell response. However, the mechanisms that govern the immunomodulatory properties of BMMSCs are still not fully elucidated. Here we show that telomerase-deficient BMMSCs lose th...

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Detalles Bibliográficos
Autores principales: Chen, Chider, Akiyama, Kentaro, Yamaza, Takayoshi, You, Yong-Ouk, Xu, Xingtian, Li, Bei, Zhao, Yimin, Shi, Songtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958307/
https://www.ncbi.nlm.nih.gov/pubmed/24401839
http://dx.doi.org/10.1002/emmm.201303000