A Functional Screen Reveals an Extensive Layer of Transcriptional and Splicing Control Underlying RAS/MAPK Signaling in Drosophila

The small GTPase RAS is among the most prevalent oncogenes. The evolutionarily conserved RAF-MEK-MAPK module that lies downstream of RAS is one of the main conduits through which RAS transmits proliferative signals in normal and cancer cells. Genetic and biochemical studies conducted over the last t...

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Detalles Bibliográficos
Autores principales: Ashton-Beaucage, Dariel, Udell, Christian M., Gendron, Patrick, Sahmi, Malha, Lefrançois, Martin, Baril, Caroline, Guenier, Anne-Sophie, Duchaine, Jean, Lamarre, Daniel, Lemieux, Sébastien, Therrien, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958334/
https://www.ncbi.nlm.nih.gov/pubmed/24643257
http://dx.doi.org/10.1371/journal.pbio.1001809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958334/
https://www.ncbi.nlm.nih.gov/pubmed/24643257
http://dx.doi.org/10.1371/journal.pbio.1001809

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