Effects of Selective and Non-Selective Glucocorticoid Receptor II Antagonists on Rapid-Onset Diabetes in Young Rats

The blockade of glucocorticoid (GC) action through antagonism of the glucocorticoid receptor II (GRII) has been used to minimize the undesirable effects of chronically elevated GC levels. Mifepristone (RU486) is known to competitively block GRII action, but not exclusively, as it antagonizes the pro...

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Detalles Bibliográficos
Autores principales: Beaudry, Jacqueline L., Dunford, Emily C., Teich, Trevor, Zaharieva, Dessi, Hunt, Hazel, Belanoff, Joseph K., Riddell, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958344/
https://www.ncbi.nlm.nih.gov/pubmed/24642683
http://dx.doi.org/10.1371/journal.pone.0091248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958344/
https://www.ncbi.nlm.nih.gov/pubmed/24642683
http://dx.doi.org/10.1371/journal.pone.0091248

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