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Mapping Network Motif Tunability and Robustness in the Design of Synthetic Signaling Circuits

Cellular networks are highly dynamic in their function, yet evolutionarily conserved in their core network motifs or topologies. Understanding functional tunability and robustness of network motifs to small perturbations in function and structure is vital to our ability to synthesize controllable ci...

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Detalles Bibliográficos
Autores principales: Iadevaia, Sergio, Nakhleh, Luay K., Azencott, Robert, Ram, Prahlad T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958390/
https://www.ncbi.nlm.nih.gov/pubmed/24642504
http://dx.doi.org/10.1371/journal.pone.0091743