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Mapping Network Motif Tunability and Robustness in the Design of Synthetic Signaling Circuits
Cellular networks are highly dynamic in their function, yet evolutionarily conserved in their core network motifs or topologies. Understanding functional tunability and robustness of network motifs to small perturbations in function and structure is vital to our ability to synthesize controllable ci...
Autores principales: | Iadevaia, Sergio, Nakhleh, Luay K., Azencott, Robert, Ram, Prahlad T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958390/ https://www.ncbi.nlm.nih.gov/pubmed/24642504 http://dx.doi.org/10.1371/journal.pone.0091743 |
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