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LKB1/AMPK and PKA Control ABCB11 Trafficking and Polarization in Hepatocytes

Polarization of hepatocytes is manifested by bile canalicular network formation and activation of LKB1 and AMPK, which control cellular energy metabolism. The bile acid, taurocholate, also regulates development of the canalicular network through activation of AMPK. In the present study, we used coll...

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Detalles Bibliográficos
Autores principales: Homolya, László, Fu, Dong, Sengupta, Prabuddha, Jarnik, Michal, Gillet, Jean-Pierre, Vitale-Cross, Lynn, Gutkind, J. Silvio, Lippincott-Schwartz, Jennifer, Arias, Irwin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958433/
https://www.ncbi.nlm.nih.gov/pubmed/24643070
http://dx.doi.org/10.1371/journal.pone.0091921