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LKB1/AMPK and PKA Control ABCB11 Trafficking and Polarization in Hepatocytes
Polarization of hepatocytes is manifested by bile canalicular network formation and activation of LKB1 and AMPK, which control cellular energy metabolism. The bile acid, taurocholate, also regulates development of the canalicular network through activation of AMPK. In the present study, we used coll...
Autores principales: | Homolya, László, Fu, Dong, Sengupta, Prabuddha, Jarnik, Michal, Gillet, Jean-Pierre, Vitale-Cross, Lynn, Gutkind, J. Silvio, Lippincott-Schwartz, Jennifer, Arias, Irwin M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958433/ https://www.ncbi.nlm.nih.gov/pubmed/24643070 http://dx.doi.org/10.1371/journal.pone.0091921 |
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