Gene Therapy for Neuropathic Pain by Silencing of TNF-α Expression with Lentiviral Vectors Targeting the Dorsal Root Ganglion in Mice

Neuropathic pain can be a debilitating condition. Many types of drugs that have been used to treat neuropathic pain have only limited efficacy. Recent studies indicate that pro-inflammatory mediators including tumor necrosis factor α (TNF-α) are involved in the pathogenesis of neuropathic pain. In t...

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Detalles Bibliográficos
Autores principales: Ogawa, Nobuhiro, Kawai, Hiromichi, Terashima, Tomoya, Kojima, Hideto, Oka, Kazuhiro, Chan, Lawrence, Maegawa, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958473/
https://www.ncbi.nlm.nih.gov/pubmed/24642694
http://dx.doi.org/10.1371/journal.pone.0092073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958473/
https://www.ncbi.nlm.nih.gov/pubmed/24642694
http://dx.doi.org/10.1371/journal.pone.0092073

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