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Fine Specificity and Molecular Competition in SLAM Family Receptor Signalling

SLAM family receptors regulate activation and inhibition in immunity through recruitment of activating and inhibitory SH2 domain containing proteins to immunoreceptor tyrosine based switch motifs (ITSMs). Binding of the adaptors, SAP and EAT-2 to ITSMs in the cytoplasmic regions of SLAM family recep...

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Detalles Bibliográficos
Autores principales: Wilson, Timothy J., Garner, Lee I., Metcalfe, Clive, King, Elliott, Margraf, Stefanie, Brown, Marion H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958483/
https://www.ncbi.nlm.nih.gov/pubmed/24642916
http://dx.doi.org/10.1371/journal.pone.0092184