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Fine Specificity and Molecular Competition in SLAM Family Receptor Signalling
SLAM family receptors regulate activation and inhibition in immunity through recruitment of activating and inhibitory SH2 domain containing proteins to immunoreceptor tyrosine based switch motifs (ITSMs). Binding of the adaptors, SAP and EAT-2 to ITSMs in the cytoplasmic regions of SLAM family recep...
Autores principales: | Wilson, Timothy J., Garner, Lee I., Metcalfe, Clive, King, Elliott, Margraf, Stefanie, Brown, Marion H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958483/ https://www.ncbi.nlm.nih.gov/pubmed/24642916 http://dx.doi.org/10.1371/journal.pone.0092184 |
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