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Heritable and inducible gene knockdown in astrocytes or neurons in vivo by a combined lentiviral and RNAi approach
Gene knockout by homologous recombination is a popular method to study gene functions in the mouse in vivo. However, its lack of temporal control has limited the interpretation of knockout studies because the complete elimination of a gene product often alters developmental processes, and can induce...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3958736/ https://www.ncbi.nlm.nih.gov/pubmed/24678290 http://dx.doi.org/10.3389/fncel.2014.00062 |